Answered questions on physiology of principles of disease block by dr Khaled A Abulfadle

Admin عدد المساهمات : 9483 تاريخ التسجيل : 06/08/2009

SEQs

1-Functions of neutrophils …………….

2-Eosinophilia occurs in ………………

3-Monocyte-macrophage system (reticuloendothelial system, RES) …………………

4-Functions of B-lymphocytes include ……………

5-Types of T-lymphocytes include ………………….

6-Define plasma, serum, homeostasis, hemostasis and thrombosis?

7-Local vascular spasm after vascular injury is caused by…………………… and it is of value in ……………………….

8-Intrinsic pathway of clot formation …………………………….

9-Fibrinolytic system ………………………..

10-Steps of hemostasis include ……………………………

11-Factors prevent intravascular clotting normally include ………………….

MCQs

1-An acute infection would show up in a blood count as…………………………
a-leukopenia.
b-too few helper T cells.
c-polycythemia.
d-leukocytosis.
e-thrombocytopenia.

2-Which of the following indicates a normal white blood cell count?
a- 1 million per mm3.
b- 15,000 per cm3.
c- 10,000 per mm3.
d- 20,000 per mm3.
e- 3,000 per mm3.

3- Which cell is not phagocytic?
a- neutrophil.
b- monocyte.
c- macrophage.
d- eosinophil.
e- basophil.

4- Antibodies are defense substances produced by the ………………… cells.
a- neutrophil.
b- monocyte.
c- B-lymphocyte.
d- eosinophil.
e- basophil.

5-Neutrophils, eosinophils and basophils are alike in that they …………………….
a- lack a defined nucleus.
b- are the only phagocytic leukocytes.
c- release histamine.
d- are granulocytes.
e- are immotile leukocytes.

6-Which WBC releases histamine at sites of inflammation?
a- neutrophil.
b- eosinophil.
c- basophil.
d- lymphocyte.
e- monocyte.

7- Antibodies can inactivate the invading agent by ………………
a- agglutination.
b- neutralization.
c- precipitation.
d- lysis.
e- all of the above.

8- Which of the following initiates the coagulation cascade in vivo?
a- Factor XII.
b- Thrombin.
c- Tissue factor.
d- Factor X.
e- Prekallikrein.

9- What does von Willebrand factor do?
a- Binds platelets to each other.
b- Binds platelets to the subendothelium.
c- Binds platelets to the phospholipid surface.
d- Carries factor VII.
e- Cleaves factor V.

10-Tissue thromboplastin is the clotting factor ……….
a- I.
b- II.
c- III.
d- IV.
e- V.

11-Calcium is the clotting factor ……….
a- I.
b- II.
c- III.
d- IV.
e- V.

Answers

[ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذه الصورة]

flower

عدد المساهمات : 12 تاريخ التسجيل : 16/12/2011

following blood vessel injury,platelets adhere to exposed subendothelial collagen and myofibrils

دكتور مافهمت هذي الجمله ممكن توضحلها لي
وجزيت خيرا

Admin عدد المساهمات : 9483 تاريخ التسجيل : 06/08/2009

This statement describes mechanism of initiation of platelet plug formation as following.....

Normally, intact endothelial lining is smooth preventing platelet's adherence and activation.

On vascular injury, the subendothelial collagen is exposed causing adherence of the platelets to it helped by both receptors on platelets and VWF causing platelet activation followed by aggregation and plug formation..............

و لكى تفهمى الموضوع أكثر قومى بالإستماع الى المحاضرة من هنا:

[ندعوك للتسجيل في المنتدى أو التعريف بنفسك لمعاينة هذا الرابط]

و بالتوفيق إن شاء الله

Smile

موضوع: hemostasis الجمعة فبراير 17, 2012 10:22 pm

فهمت دكتور يعني injury تطلع مواد تساعد على التصاق platetes و coagualtive factors وتسوي plug بالاخيرر

بس ابي اعرف دكتور متى اقول انه هذا tissue صار فيه thrombus او clot

ما معني recanaliztion ?

وهل clotting factor يعتبر انزيم او لا ؟

Admin عدد المساهمات : 9483 تاريخ التسجيل : 06/08/2009

Clot formation: occurs in injured vessel and it is a physiological process aims to stop bleeding.

Thrombosis: occurs in intact vessel and it is a pathological process that may obstruct a vessel and it may occur in conditions like atherosclerosis.

Recanalization: means to reopen the vessel i.e. after clot formation and healing of vessel wall, fibrinolytic system dissolves the clot to return it it to previus normal condition.

Most of clotting factors are considered as proteolytic enzymes, but others are considered as cofactors as calcium i.e. factor IV

You are welcome for any question.

Good luck

Smile

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